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On July 10, 2018, in Washington, DC, the Johns Hopkins Center for Health Security hosted a meeting on global health security in South Asia. The goal of the meeting was to discuss health security challenges in South Asia and to identify opportunities for implementation of health security initiatives. The speakers included high-level participants from the government of Pakistan, the World Bank, the US Centers for Disease Control and Prevention, the US Department of Health and Human Services, the US National Academies of Science, and from other academic, nonprofit, and government organizations. The meeting was sponsored by the Project on Advanced Systems and Concepts for Countering WMD (PASCC; sponsored by the Defense Threat Reduction Agency, DTRA) of the US Air Force Institute for National Security Studies. The highly interactive meeting presented an important opportunity to focus on the health security challenges facing South Asia and to identify paths forward, and it emphasized the importance of dialogue in bringing together multiple disciplines, sectors, and countries, extending even beyond the region. As one participant noted, “A health risk anywhere is a health risk everywhere.” This document is a summary report of the meeting discussions.