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Clade X Exercise

The Center hosted a pandemic tabletop exercise in Washington, D.C., in May 2018. The goal of this exercise (“Clade X”) was to illustrate high-level strategic decisions and policies that the United States and the world will need to pursue in order to diminish the consequences of a severe pandemic. It addressed a pressing current concern, present plausible solutions, and be experientially engaging.


Clade X was designed for national decision-makers in the thematic biosecurity tradition of the Center’s two previous exercises, Dark Winter (2001) and Atlantic Storm (2005). The day-long exercise simulated a series of Cabinet meetings among prominent players who previously occupied similar leadership positions in past Presidential administrations. Players were presented with a scenario that highlighted unresolved real-world policy issues that could be solved with sufficient political will and attention now and into the future.

Lessons learned from Clade X will be shared broadly to raise awareness of key pandemic prevention and response challenges.

Project team leads: Eric Toner, MD

Project team: Tom Inglesby, MD; Anita Cicero, JD; Randy Larsen USAF (retired); Crystal Watson, DrPH, MPH; Gigi Kwik Gronvall, PhD; Jennifer Nuzzo, DrPH, SM; Monica Schoch-Spana, PhD; Tara Kirk Sell, PhD, MA; Amesh Adalja, MD; Caitlin Rivers, PhD, MPH; Christopher Hurtado, MHS; Diane Meyer RN, MPH; Sanjana Ravi, MPH; Matthew Shearer, MPH; Michael Snyder, MALD; Matthew Watson; Richard E. Waldhorn, MD; Jackie Fox; Andrea Lapp; Nick Alexopulos; Julia Cizek

Project supported by: Open Philanthropy Project



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