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Our publications keep professionals working across the public, private, and academic sectors informed on the most important developments and issues in health security and biosecurity.

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Title:

A Plague on Your City: Observations from TOPOFF

Authors:
Thomas V. Inglesby, Rita Grossman, and Tara O'Toole
Date posted:
February 01, 2001
Publication type:
Article
Publication:

Clin Infect Dis 2001;32(3):436-445

Publisher:
Oxford University Press
Availability:
Available on publisher's website
See also:

Full article as HTML • PDF

Introduction:

The United States Congress directed the Department of Justice to conduct an exercise engaging key personnel in the management of mock chemical, biological, or cyberterrorist attacks. The resulting exercise was called "TOPOFF," named for its engagement of top officials of the United States government. This article offers a number of medical and public health observations and lessons discovered during the bioterrorism component of the exercise. The TOPOFF exercise illuminated problematic issues of leadership and decision-making; the difficulties of prioritization and distribution of scarce resources; the crisis that contagious epidemics would cause in health care facilities; and the critical need to formulate sound principles of disease containment. These lessons should provoke consideration of future directions for bioterrorism planning and preparedness at all levels of government and among the many communities and practitioners with responsibilities for national security and public health.

Full article as HTML • PDF

 

 

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