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Antibiotic Consumption and Stewardship at a Hospital outside of an Early Coronavirus Disease 2019 Epicenter

Deanna J. Buehrle, Brooke K. Decker, Marilyn M. Wagener, Amesh Adalja, Nina Singh, Mary C. McEllistrem, M. Hong Nguyen, Cornelius J. Clancy
Date posted:
August 19, 2020
Publication type:
Antimicrob Agents Chemother. 2020 Oct 20;64(11):e01011-20
American Society for Microbiology
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There are scant data on the impact of coronavirus disease 2019 (COVID-19) on hospital antibiotic consumption, and no data from outside epicenters. At our nonepicenter hospital, antibiotic days of therapy (DOT) and bed days of care (BDOC) were reduced by 151.5/month and 285/month, respectively, for March to June 2020 compared to 2018–2019 (P = 0.001 and P < 0.001). DOT per 1,000 BDOC was increased (8.1/month; P = 0.001). COVID-19 will impact antibiotic consumption, stewardship, and resistance in ways that will likely differ temporally and by region.



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